Hospital Clínic - (IDIBAPS)
The AIDS Research Group (IDIBAPS / Hospital Clinic) is composed by 10 teams that conduct research centered on the Human Immunodeficiency Virus (HIV) and AIDS disease from different standpoints. This area carries out a wide range of activities, which are divided up into two parts: Clinical researches focused on efficacy and tolerance of antiretrovirals, on resistance mechanisms and opportunistic infections and coinfections; Basic researches focused on retrovirology and viral immunopathology, including vaccine development. HIV clinical research started in 1985 when the first cases of HIV infection were detected in Spain. Our group has paid a pivotal role, both at a national and at international level, in the development of prevention and treatment strategies for the HIV and opportunistic infections and coinfections. The HIV research laboratory was founded more than 20 years ago (1995), initially with the purpose of supporting the clinical research activities and later on to develop its own more basic projects. The main research lines are: cohort studies, early and advanced HIV infection, tuberculosis and other opportunistic infections, solid organ transplantation in HIV, immunopathogenesis, microbiome and clinical trials with therapeutic and preventive vaccines, other strategies of prevention, long-term non progressors and elite controllers, coinfection with hepatitis B and C, pharmacokinetics, resistance to antiretrovirals, STI and papillomavirus infections in HIV, efficacy and tolerability of antiretroviral therapy, epidemiology, prevention and management of non-AIDS events, HYV immunopathology and cellular immunology, HIV humoral immunity, reservoir and development of new HIV-1 immunogens, development of new preventive vaccines and AIDS genomics and pharmacogenomics.