WP3's trials
Interventional studies of safety and proof of concept of drugs for intensification, eradication and immunogens for potential therapeutic or preventive vaccine candidates
RIS-VAC25. SCRAtCH Study.
Study to assess microbiota composition as a feasible screening method for anal cancer in HIV infected patients.
Leader Researcher: Sergio Serrano.
Sponsor: Instituto de Investigación Sanitaria del Hospital Ramón y Cajal.
Status: Pending.
RIS-VAC24. GARDANIL Study.
Study to assess immunogenicity of the nonavalent vaccine against human papillomavirus virus in HIV infected men who have sex with men (MSM)
Leader Researcher: Sergio Serrano, JA Pérez-Molina.
Sponsor: Fundación SEIMC-GESIDA.
Status: Pending.
RIS-VAC-022. ANHIVAC Study.
Study to assess safety and effectiveness of the combination of a therapeutic vaccine (MVA-B) plus 3BNC117 bNAb with Romidepsin in HIV chronically infected patients under stable combination antiretroviral therapy.
Leader Researcher: Felipe García.
Sponsor: IDIBAPS.
Status: Completed.
RIS-VAC23. RIS-VAC23 Study.
Study to assess changes in bacterial translocation and immunological activation in HIV infected patients after going through a supplemented mediterranean diet.
Leader Researcher: Felipe García.
Sponsor: Fundació Clínic Recerca Biomédica.
Status: Pending.
RIS-VAC-021. iHIVaRNA Study.
Study to assess the effect of the therapeutic vaccine based on TriMix / RNAm in HIV-1 chronically infected patients under antiretroviral therapy. iHIVARNA Phase IIa
Leader Researcher: Felipe García.
Sponsor: Fundació Clínic Recerca Biomédica.
Status: Completed.
RIS-VAC-020. iHIVaRNA Study.
Study to assess safety of iHIVARNA-01 vaccine in HIV infected patients under stable antiretroviral therapy.
Leader Researcher: Felipe García.
Sponsor: Fundació Clínic Recerca Biomédica.
Status: Completed.
RIS-VAC-019. RIS-VAC-019 Study.
Study to analyse the impact of Dasatinib plus antiretroviral therapy in the viral reservoir in patients with acute/recent HIV-1 infection.
Leader Researcher: José M. Miró.
Sponsor: IDIBAPS.
Status: Pending.
RIS-EST-VAC18. BCN02-ROMI Study.
Study to assess safety of a booster of an experimental vaccine with a drug (Romidepsina) able to activate the integrated virus in resting cells (reservoir) and the effect in the control of the infection after a controlled antiretroviral therapy interruption.
Leader Researcher: Bea Mothe, José M Miró.
Sponsor: Fundació Lluita Contra la SIDA.
Status: Completed.
RIS-EST-VAC17. ChAd-MVA.HIVconsv-BCN01 Study.
Study to assess safety and effect on immune system of two new therapeutic vaccines against HIV administered by intramuscular route with two different treatment regimens.
Leader Researcher: Bea Mothe, José M Miró.
Sponsor: Fundació Lluita Contra la SIDA.
Status: Completed.
RIS-EST-VAC16. REFRESH Study.
Study to assess the effects of a microbiota transplantation at low and frequent dosages for 8 weeks in the immunological system of HIV infected patients receiving antiretroviral therapy.
Leader Researcher: Sergio Serrano Villar.
Sponsor: Instituto de Investigación Sanitaria del Hospital Ramón y Cajal.
Status: Completed.
EST-VAC-15. EST-VAC-15 Study.
Study to assess the antiretroviral activity and the impact in the viral reservoir of Dasatinib in HIV infected patients.
Leader Researcher: Josep María Miró.
Sponsor: IDIBAPS.
Status: Pending.
RIS-EST-VAC44. PROMALTIA Study.
Assessment the effects of an immunomodulatory nutritional intervention in the immunological recovery of late diagnosed HIV patients.
Leader Researcher: Sergio Serrano Villar, Vicente Estrada.
Sponsor: Fundación de Investigación Sanitaria, Hospital Clínico San Carlos.
Status: Completed.