INTRODUCCION WP3

Interventional studies of safety and proof of concept of drugs for intensification, eradication and immunogens for potential therapeutic or preventive vaccine candidates

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RIS-VAC25. SCRAtCH Study.

Study to assess microbiota composition as a feasible screening method for anal cancer in HIV infected patients. 

Leader Researcher: Sergio Serrano.

Sponsor: Instituto de Investigación Sanitaria del Hospital Ramón y Cajal.

Status: Pending.

RIS-VAC24. GARDANIL Study.

Study to assess immunogenicity of the nonavalent vaccine against human papillomavirus virus in HIV infected men who have sex with men (MSM)
 

Leader Researcher: Sergio Serrano, JA Pérez-Molina.

Sponsor: Fundación SEIMC-GESIDA.

Status: Pending.

RIS-VAC-022. ANHIVAC Study.

Study to assess safety and effectiveness of the combination of a therapeutic vaccine (MVA-B) plus 3BNC117 bNAb with Romidepsin in HIV chronically infected patients under stable combination antiretroviral therapy.
 

Leader Researcher: Felipe García.

Sponsor: IDIBAPS.

Status: Completed.

RIS-VAC23. RIS-VAC23 Study.

Study to assess changes in bacterial translocation and immunological activation in HIV infected patients after going through a supplemented mediterranean diet.
 

Leader Researcher: Felipe García.

Sponsor: Fundació Clínic Recerca Biomédica.

Status: Pending.

RIS-VAC-021. iHIVaRNA Study.

Study to assess the effect of the therapeutic vaccine based on TriMix / RNAm in HIV-1 chronically infected patients under antiretroviral therapy. iHIVARNA Phase IIa
 

Leader Researcher: Felipe García.

Sponsor: Fundació Clínic Recerca Biomédica.

Status: Completed.

RIS-VAC-020. iHIVaRNA Study.

Study to assess safety of iHIVARNA-01 vaccine in HIV infected patients under stable antiretroviral therapy. 
 

Leader Researcher: Felipe García.

Sponsor: Fundació Clínic Recerca Biomédica.

Status: Completed.

RIS-VAC-019. RIS-VAC-019 Study.

Study to analyse the impact of Dasatinib plus antiretroviral therapy in the viral reservoir in patients with acute/recent HIV-1 infection. 
 

Leader Researcher: José M. Miró.

Sponsor: IDIBAPS.

Status: Pending.

RIS-EST-VAC18. BCN02-ROMI Study.

Study to assess safety of a booster of an experimental vaccine with a drug (Romidepsina) able to activate the integrated virus in resting cells (reservoir) and the effect in the control of the infection after a controlled antiretroviral therapy interruption.
 

Leader Researcher: Bea Mothe, José M Miró.

Sponsor: Fundació Lluita Contra la SIDA.

Status: Completed.

RIS-EST-VAC17. ChAd-MVA.HIVconsv-BCN01 Study.

Study to assess safety and effect on immune system of two new therapeutic vaccines against HIV administered by intramuscular route with two different treatment regimens. 
 

Leader Researcher: Bea Mothe, José M Miró.

Sponsor: Fundació Lluita Contra la SIDA.

Status: Completed.

RIS-EST-VAC16. REFRESH Study.

Study to assess the effects of a microbiota transplantation at low and frequent dosages for 8 weeks in the immunological system of HIV infected patients receiving antiretroviral therapy.  
 

Leader Researcher: Sergio Serrano Villar.

Sponsor: Instituto de Investigación Sanitaria del Hospital Ramón y Cajal.

Status: Completed.

EST-VAC-15. EST-VAC-15 Study.

Study to assess the antiretroviral activity and the impact in the viral reservoir of Dasatinib in HIV infected patients.  
 

Leader Researcher: Josep María Miró.

Sponsor: IDIBAPS.

Status: Pending.

RIS-EST-VAC44. PROMALTIA Study.

Assessment the effects of an immunomodulatory nutritional intervention in the immunological recovery of late diagnosed HIV patients.
 

Leader Researcher: Sergio Serrano Villar, Vicente Estrada.

Sponsor: Fundación de Investigación Sanitaria, Hospital Clínico San Carlos.

Status: Completed.